首页|透明质酸敷料联合吡美莫司乳膏治疗面部敏感性皮肤的临床疗效

透明质酸敷料联合吡美莫司乳膏治疗面部敏感性皮肤的临床疗效

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目的 探究透明质酸敷料与吡美莫司乳膏联合治疗方案用于面部敏感性皮肤病中的应用效果.方法 选取2021年1月—2023年1月本院收治的60例面部敏感性皮肤患者为研究对象,并按照随机数字法将其分为两组,每组各30例,参照组采用吡美莫司软膏治疗,研究组则以此为治疗基础,联合透明质酸敷料进行医治,观察并分析两组治疗不同时期的皮肤瘙痒(SP)、烧灼感(SB)、面部红斑、纹理与毛孔等面部敏感状态变化状况,以及患者面部皱纹(FWS)、生活质量(DLQI)改善效果与不良反应发生情况.结果 两组治疗前SP、SB、FWS、DLQL评分、面部红斑、纹理、毛孔评分与组间不良反应发生率对比,差异无统计学意义(P>0.05);研究组治疗6周后的SP、SB评分、面部红斑、毛孔及纹理评分、FWS评分、DLQI评分与参照组对比均较低,组间对比差异有统计学意义(P<0.05).结论 采用吡美莫司软膏与透明质酸敷料联合治疗面部敏感性皮肤疾病,不仅可以有效缓解患者的皮肤瘙痒、烧灼感,且对患者的皮肤红斑、毛孔等敏感状态和面部皱纹、生活质量状况也有良好的改善作用,还不易引发不良反应,具有较高的治疗安全性,适合用于临床推广.
Clinical Curative Effect of Hyaluronic Acid Dressings Combined with Pembrolimus Cream in Treatment of Sensitive Facial Skin
Objective To explore application effect of combination therapy of hyaluronic acid dressings and Pimecrolimus Cream in treatment of facial sensitive skin diseases.Methods The paper chose 60 patients with facial sensitive skin from January 2021 to January 2023,and divided them into two groups randomly,with 30 cases in each group.Control group was treated with Pimecrolimus Cream,while study group with hyaluronic acid dressings as the basis.Changes in facial sensitive states including skin itching(SP),burning sensation(SB),facial erythema,texture,and pores,improvement effect and incidence of adverse reactions of patients with facial wrinkles(FWS)and life quality(DLQI)were observed and analyzed at different stages of treatment between two groups.Results There was no significant difference in incidence of adverse reactions between two groups in terms of SP,SB,FWS,DLQL scores,facial erythema,texture,and pore scores before treatment(P>0.05).However,after 6 weeks of treatment,SP,SB scores,facial erythema,pore and texture scores,FWS scores,and DLQI scores of study group were lower than reference group,data difference between groups was significant(P<0.05).Conclusion Combination of Pimecrolimus Cream and hyaluronic acid dressing can alleviate skin itching and burning sensation of patients with sensitive facial skin diseases effectively,with good improvement effect on sensitive skin conditions including redness and pores,facial wrinkles,and life quality.It is not likely to cause adverse reactions with high treatment safety,which is suitable for clinical promotion.

Hyaluronic acid dressingsPimecrolimus CreamFacial sensitive skinClinical effect

付木兰、朱文艳

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南通大学附属医院 皮肤科,江苏 南通 226001

透明质酸敷料 吡美莫司软膏 面部敏感性皮肤 临床效果

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(8)
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