Clinical Comparison of Nadroparin Calcium and Daxaparin Sodium in Preventing Lower Limb Deep Vein Thrombosis After Hip and Knee Arthroplasty
Objective To compare effect of nadroparin calcium and daxaparin sodium in preventing lower limb deep vein thrombosis after hip and knee arthroplasty.Methods The paper reviewed and analyzed 60 patients with hip and knee replacement surgery in our hospital from March 2020 to March 2022 as study subjects.According to the inclusion and exclusion criteria,30 cases in control group were treated with nadroparin calcium to prevent deep vein thrombosis in the lower limbs;30 cases in study group with daxaparin sodium to prevent deep vein thrombosis in the lower limbs.Incidence of postoperative deep vein thrombosis and results of various postoperative indicators were evaluatedbetween two groups.Results Incidence of lower limb deep vein thrombosis in control group was higher than study group,there was statistically significant difference between the groups(P<0.05).Difference in intraoperative blood loss and drainage volume between two groups was statistically significant(P<0.05),and degree of hemoglobin reduction between study group and control group was statistically significant(P<0.05).There was no statistically significant difference in PT and APTT levels between two groups before and after surgery(P>0.05).Conclusion Daxaparin sodium and nadroparin calcium can effectively control incidence of deep vein thrombosis in the lower limbs,but daxaparin sodium is more conducive to reducing formation of deep vein thrombosis in the lower limbs.
Daxaparin sodiumNatroparin calciumHip and knee joint surgeryLower limb deep vein thrombosisEffect analysis
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