首页|小儿支原体肺炎的阿奇霉素序贯疗法结合加味麻杏石甘汤治疗作用

小儿支原体肺炎的阿奇霉素序贯疗法结合加味麻杏石甘汤治疗作用

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目的 探讨小儿支原体肺炎的阿奇霉素序贯疗法结合加味麻杏石甘汤的应用价值。方法 选取2020年8月—2022年12月本院收治的支原体肺炎患儿62例为研究对象,按照随机分组法分为A组和B组,每组31例。A组使用阿奇霉素序贯疗法基础上施用加味麻杏石甘汤,B组使用阿奇霉素序贯疗法。对比两组临床疗效、临床症状改善情况、白细胞介素-6(IL-6)、肿瘤坏死因子(TNF-α)、T淋巴细胞亚群(CD3+、CD4+)等结果。结果 A组总有效率高于B组,组间差异有统计学意义(P<0。05);A组咳嗽痰鸣消失、体温恢复及干湿啰音消失时间短于B组,组间差异有统计学意义(P<0。05);治疗后,A组IL-6、TNF-α水平低于B组,组间差异有统计学意义(P<0。05);治疗后,A组CD3+、CD4+水平高于B组,组间差异有统计学意义(P<0。05);A组不良反应发生率低于B组,组间差异有统计学意义(P<0。05)。结论 支原体肺炎患儿应用阿奇霉素序贯疗法结合加味麻杏石甘汤,可提高临床疗效、免疫功能,缩短临床症状改善时间,缓解炎症,存在用药安全性。
Curative Effect of Azithromycin Sequential Therapy Combined with Modified Ephedra,Apricot Kernel,Gypsum and Licorice Decoction on Pediatric Mycoplasma Pneumonia
Objective To explore application value of azithromycin sequential therapy combined with modified ephedra,apricot kernel,gypsum and licorice decoction for children with mycoplasma pneumonia.Methods The paper chose 62 children with mycoplasma pneumonia in our hospital from August 2020 to December 2022,and divided them into group A and B randomly,with 31 cases in each group.Group A was treated with sequential therapy with azithromycin,while group B with modified ephedra,apricot kernel,gypsum and licorice decoction on the basis.Clinical Effect,improvement of clinical symptoms,interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α),results of T lymphocyte subsets(CD3+,CD4+)were compared between two groups.Results Total effective rate of group A was higher than group B(P<0.05).The disappearance time of cough and phlegm,temperature recovery,and dry and wet rales in group A was shorter than group B(P<0.05).After treatment,levels of IL-6 and TNF-αin group A was lower than group B(P<0.05).After treatment,levels of CD3+and CD4+in group A were higher than group B(P<0.05).Incidence of adverse reactions in group A was lower than group B(P<0.05).Conclusion Sequential therapy with azithromycin combined with modified ephedra,apricot kernel,gypsum and licorice decoction can improve clinical effect,immune function,shorten time for clinical symptom improvement,alleviate inflammation of children with mycoplasma pneumonia,with medication safety.

Mycoplasma pneumoniaChildrenAzithromycinEphedra,apricot kernel,gypsum and licorice decoction

黄芹、魏华

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南充市中医医院,四川 南充 637000

支原体肺炎 小儿 阿奇霉素 加味麻杏石甘汤

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(9)
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