首页|基于过敏原检测分析儿童变应性鼻炎脱敏治疗的疗效评估

基于过敏原检测分析儿童变应性鼻炎脱敏治疗的疗效评估

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目的 分析儿童变应性鼻炎(AR)的过敏原检测情况,并对脱敏治疗的治疗效果进行评估。方法 选择2018年9月—2020年9月就诊的78例AR患儿为研究对象,对患儿均予以过敏原检测,分析过敏原检测情况。针对患儿均予以皮下注射安脱达(屋尘螨变应原制剂,ALK-ABELLO A/S)脱敏治疗,对患儿治疗前1d、治疗1年后、治疗2年后的症状评分、药物评分、生活质量评分进行评价。结果 经过敏原检测,78例AR患儿均为螨类过敏;2级、3级总数40例,经脱敏治疗下降1级、4级、5级经脱敏治疗下降1~2级。78例患儿在经治疗1年后、治疗2年后的症状评分、药物评分、生活质量评分相较治疗前1d均降低,对比差异有统计学意义(P<0。05)。结论 儿童AR的过敏原以屋尘螨、粉尘螨为主,对于患儿采取脱敏治疗,可有效缓解患儿临床症状,提高其生活质量。
Effect Evaluation and Study of Desensitization Treatment for Allergic Rhinitis of Children Based on Allergen Detection Analysis
Objective To explore allergen detection of allergic rhinitis(AR)of children and evaluate curative effect of desensitization therapy.Methods The paper chose 78 pediatric patients with AR in the hospital from September 2018 to September 2020 as research subjects,treated with allergen testing,and analyzed results of allergen testing.All cases were treated with subcutaneous injection of antelda(house dust mite allergen preparation,ALK-ABELLO A/S)for desensitization.Symptom scores,medication scores,and life quality scores of patients were evaluated 1 day before treatment,1 year after treatment,and 2 years after treatment.Results 78 children with AR were mite allergy based on allergen testing,including 40 cases of grade 2 and grade 3,which decreased by 1 grade after desensitization treatment.Grade 4 and grade 5 decreased by 1~2 grades after desensitization treatment.Symptom scores,medication scores,and life quality scores of 78 pediatric patients were lower after 1 year and 2 years of treatment than before treatment,difference was statistically significant(P<0.05).Conclusion AR allergens of children are mainly house dust mites and dermatophagoides farinae,desensitization treatment can effectively improve clinical symptoms and life quality of children.

ChildrenAllergic rhinitisDesensitization treatmentAllergen monitoringCurative effect

孙文玥、陈敬滨、曹姝平

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广州市越秀区儿童医院,广东 广州 510091

儿童 变应性鼻炎 脱敏治疗 过敏原监测 疗效

广东省卫生经济学会2023年度科研课题

2023-WJMZ-69

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(10)