Clinical Effect Comparison of Levofloxacin Triple Therapy and Amoxicillin Triple Therapy in Treatment of Gastric Ulcers
Objective To compare effect of levofloxacin triple therapy and amoxicillin triple therapy on effect of peptic ulcers.Methods The paper chose 74 patients with peptic ulcers in our hospital from February 2022 to February 2023 as research subjects,and divided them into two groups according to random number table method,with 37 cases in each group.Group A was treated with amoxicillin triple therapy,while group B with levofloxacin triple therapy.Curative effect,inflammatory factors,and total adverse reaction rate were compared between two groups.Results Total effective rate of group B was higher than group A(P<0.05).Concentration of TNF-α,TGF-β,IL-6 after treatment in group A and group B was lower than before treatment,while concentration of EGF was higher than before treatment(P<0.05).Concentration of TNF-α,TGF-β,IL-6 was lower in group B(P<0.05),and EGF concentration was higher in group B(P<0.05).Incidence of adverse reactions in group B was lower(P<0.05).Conclusion The triple therapy of levofloxacin can achieve good curative effect on peptic ulcers,with low adverse reactions,high safety,can reduce inflammatory reactions,which has good clinical application value.
万方数据
维普
