Clinical Effect of Sequential Therapy with Azithromycin for Children with Mycoplasma Pneumonia and Its Effect on Serum CRP
Objective To evaluate application of sequential therapy with azithromycin for children with mycoplasma pneumonia and its intervention effect on serum CRP.Methods The paper reviewed and analyzed medical data of 77 children with mycoplasma pneumonia in the local area.Firstly,it retrieved data of the affected children and divided them into groups according to different diagnosis and treatment,2 groups totally.Basic interventions of two groups of children were the same,37 cases in control group were treated with intravenous infusion of azithromycin,40 children in observation group with sequential therapy with azithromycin.Both groups had a medication course of 2 weeks.Clinical effect of patients was evaluated,serum C-reactive protein(CRP)index by blood collection before intervention,1 week of intervention,and 2 weeks of intervention was detected.Results Effective rate in control group(83.78%)was lower than observation group(97.50%),comparison was statistically significant(P<0.05).Comparison of serum CRP levels between two groups before intervention was not statistically significant(P>0.05).The serum CRP levels between two groups after intervention for 1 week and 2 weeks were lower than before(P<0.05),decrease degree of serum CRP levels in observation group was better than control group,with statistical significance(P<0.05).Conclusion Azithromycin sequential therapy can further improve effect of children with mycoplasma pneumonia,reduce secretion of pro-inflammatory factors,and alleviate symptoms.
万方数据
维普
