摘要
目的 探讨胺碘酮联合美托洛尔治疗快速心律失常的临床疗效.方法 选取2019年1月—2023年7月在本院诊治的100例快速心律失常患者为研究对象,并随机分为对照组和观察组,每组50例.其中,对照组采用胺碘酮进行治疗,观察组采用胺碘酮联合美托洛尔,比较两组患者的治疗效果.结果 观察组治疗效果优于对照组,组间差异有统计学意义(P<0.05).观察组不良反应低于对照组,组间差异有统计学意义(P<0.05).治疗前,两组心功能指标对比,差异无统计学意义(P>0.05);治疗后,观察组心功能指标显著优于对照组,组间差异有统计学意义(P<0.05).治疗后,观察组的QT离散度优于对照组,组间差异有统计学意义(P<0.05).结论 联合应用胺碘酮与美托洛尔进行治疗,可显著降低快速心律失常患者的不良反应发生率,并有效改善其心功能状况.
Abstract
Objective To evaluate practical application effect of amiodarone combined with metoprolol in treatment of patients with rapid arrhythmia.Methods The paper chose 100 patients with tachyarrhythmias in our hospital from January 2019 to July 2023,and divided them into control group and observation group randomly with 1:1 equal distribution method,with 50 cases in each group.Control group was treated with amiodarone,and observation group with amiodarone combined with metoprolol.Curative effect was compared between two groups.Results Curative effect of observation group was better than control group(P<0.05),adverse reactions of observation group were lower than control group(P<0.05).Difference in cardiac function indicators between two groups before treatment was comparable(P>0.05).After treatment,cardiac function indicators of observation group were significantly better than control group(P<0.05).After treatment,QT dispersion of observation group was better than control group,with significant difference(P<0.05).Conclusion Combination drug therapy(amiodarone,metoprolol)can reduce adverse drug reactions and improve cardiac function of patients with rapid arrhythmia effectively.
维普
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