Diagnostic value of CA12-5 combined with mycobacterium tuberculosis detection in menstrual blood in female reproductive system tuberculosis
Objective To investigate fluorescent quantitative PCR(FQ-PCR)detection of mycobacterium tuberculosis in menstrual blood combined with serum carbohydrate antigen 12-5(CA-12-5)for female genital tuberculosis(female genital tuberculosis)Diagnostic value of tuberculosis(FGT).Methods Clinical examination data of 160 cases of tubal infertility with unknown causes admitted to our hospital from January 2018 to December 2021 were retrospectively analyzed.FQ-PCR and serum CA12-5 content(<35U/L)in menstrual blood were analyzed based on endoscopic findings and pathological findings.At the same time,the positive rate and detection time of FQ-PCR were compared with that of serum mycobacterium tuberculosis.The Results The missed diagnosis rate of genital tuberculosis by FQ-PCR combined with CA12-5 was 12.82%,which was lower than 64.10%by FQ-PCR alone,35.90%by CA12-5 and 7.18%by FQ-PCR in serum.Meanwhile,the combined detection time was lower than that of routine examination(culture and thoracoscopic examination)(both P<0.05).Conclusion Compared with a single detection method,FQ-PCR combined with Wai-Qing CA12-5 has higher diagnostic efficiency in the diagnosis of female genital tuberculosis,lower missed diagnosis rate and less detection time,which has certain clinical practical value.
female reproductive system tuberculosisBacillus tuberculosis of menstrual bloodCarbohydrate antigen 12-5Diagnostic valueTubal infertilityFluorescence quantification
万方数据
维普
