Research Progress on FKBPL,A New Member of Immune Affinity Protein Family
FKBPL is a novel immune affinity protein which has been clinically applied in treatment of numerous diseases.It can inhibits tumor growth and metastasis effectively,regulate estrogen receptor signaling,which plays decisive role in response to endocrine therapy.Moreover,FKBPL can regulate pathological angiogenesis of cardiac dysfunction,which can be beneficial to effective improvement of angiogenesis and endothelial function in treatment of diabetes patients during pregnancy through down-regulation.FKBPL-CD44 pathway also plays a crucial role in risk stratification of preeclampsia and mesenchymal stem cell therapy.Based on this,the article related research progress of FKBPL as immunoaffinity protein in treatment of clinical diseases,hope to be helpful.
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