Curative Effect Observation of Qubai babuqi Tablets Combined with Prednisolone Acetate on Rapidly Progressive Segmental Vitiligo
Objective To observe curative effect of Qubai babuqi tablets combined with prednisolone acetate for rapidly progressive segmental vitiligo.Methods The paper chose 62 patients with rapidly progressive segmental vitiligo in our hospital from March 2020 to December 2022,and divided them into two groups with random number table method.Single drug group was treated with prednisolone acetate tablets only(31 cases),while combination group with Qubai babuqi tablets on the basis of single drug group(31 cases).Skin lesion area,color recovery time,effect,laboratory indicators,inflammatory factors,life quality,and incidence of adverse reactions were compared between two groups.Results After treatment,skin lesion area in combination group was significantly smaller than single drug group,and duration of skin lesion discoloration was longer than single drug group.Total effective rate of combination group was significantly higher than single drug group.After combined treatment,levels of white blood cell count(WBC)and platelet lymphocyte ratio(PLR)in combination group were higher than single drug group,while levels of interleukin-6(IL-6)and interleukin-17(IL-17)were significantly lower than single drug group.Scores of all dimensions of Simplified Life quality Scale(SF-36)in combination group after treatment were higher than single drug group,and difference was statistically significant(P＜0.05).There was no statistically significant difference in incidence of adverse reactions between single drug group and combination group(12.90％vs 22.58％)(P＞0.05).Conclusion Combination of Qubai babuqi tablets and prednisolone acetate can achieve definite curative effect for rapidly progressive segmental vitiligo in clinical practice.
万方数据
维普
