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后腹腔镜下肾部分切除术治疗T1期肾癌的临床疗效分析

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目的 分析后腹腔镜下肾部分切除术治疗T1期肾癌的临床疗效。方法 选取2018年3月-2022年7月本院T1期肾癌患者86例为研究对象,并按随机数字表法分为观察组和对照组,每组43例。其中,对照组采用后腹腔镜根治性肾切除术,观察组采用后腹腔镜下肾部分切除术。对比两组围手术期情况、肾功能[尿素氮(BUN)、血肌酐(Scr)]、并发症发生率、远期疗效(局部复发、远处转移)。结果 两组术后引流管拔出时间、术后进食时间对比,差异无统计学意义(P>0。05);观察组手术时间较对照组长,术中出血量较对照组多,组间差异有统计学意义(P<0。05)。术后6个月,观察组BUN、Scr较对照组低,组间差异有统计学意义(P<0。05)。两组并发症发生率对比,差异无统计学意义(P>0。05)。两组局部复发率、远处转移率对比,差异无统计学意义(P>0。05)。结论 后腹腔镜下肾部分切除术治疗T1期肾癌患者,会一定程度延长手术时间、增加术中出血量,但未明显增加手术风险和局部复发、远处转移风险,且对远期肾功能影响更小,利于改善预后。
Clinical Effect Analysis of Retroperitoneal Laparoscopic Partial Nephrectomy in Treatment of T1 Stage Renal Cell Carcinoma
Objective To analyze clinical effect of retroperitoneal laparoscopic partial nephrectomy in treatment of T1 stage renal cell carcinoma.Methods The paper chose 86 patients with T1 stage renal cell carcinoma in our hospital from March 2018 to July 2022,and divided them into observation group and control group with random number table method,with 43 cases in each group.Control group was treated with retroperitoneal laparoscopic radical nephrectomy,while observation group with retroperitoneal laparoscopic partial nephrectomy.Perioperative conditions,renal function(BUN,Scr),incidence of complications,and long-term effect(local recurrence,distant metastasis)were compared between two groups.Results There was no significant difference between two groups in terms of postoperative drainage tube extraction time and postoperative feeding time,(P>0.05).Observation group had longer surgical time and more intraoperative bleeding than control group(P<0.05).After 6 months of surgery,BUN and Scr in observation group was lower than control group(P<0.05).There was no significant difference in incidence of complications between two groups(P≥0.05).There was no significant difference in local recurrence rate and distant metastasis rate between two groups(P>0.05).Conclusion Retroperitoneal laparoscopic partial nephrectomy can prolong surgical time and increase intraoperative bleeding of T1 stage renal carcinoma patients to a certain extent,but it does not increase risks of surgery,local recurrence and distant metastasis significantly,with low effect on long-term renal function,which is beneficial for improving prognosis.

Renal carcinomaRetroperitoneal laparoscopic partial nephrectomyRadical nephrectomy

韦明慧

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广西贵港市第二人民医院泌尿外科,广西 贵港 537132

肾癌 后腹腔镜下肾部分切除术 根治性肾切除术

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(13)