首页|视网膜光凝加康柏西普玻璃体内注射用于糖尿病视网膜病变的临床研究

视网膜光凝加康柏西普玻璃体内注射用于糖尿病视网膜病变的临床研究

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目的 观察全视网膜光凝(PRP)加康柏西普玻璃体内注射治疗糖尿病视网膜病变(DR)的疗效.方法 研究时间设定为2019年5月-2021年5月,地点在临沂市中心医院,研究对象为本院收治的100例糖尿病视网膜病变患者.患者均接受PRP治疗,按随机数字表法分为试验组(50例)与对照组(50例),对照组患者仅接受全视网膜光凝(PRP)治疗,试验组在全视网膜光凝(PRP)基础上再给予玻璃体腔注射康柏西普治疗.治疗前以及治疗4周后,分别测量两组患者的眼内压、最佳矫正视力、黄斑中心凹厚度,对数据进行比较.结果 在接受治疗4周之后,试验组患者患眼矫正视力情况明显好于对照组,组间差异显著,具有统计学意义(P<0.001);试验组患者眼黄斑中心凹厚度与对照组相比,数值更低,组间差异显著,具有统计学意义(P<0.05);在治疗4周之后,两组患者的患眼眼压对比无明显差异,不具有统计学意义(P>0.05).结论 康柏西普玻璃体腔注射联合全视网膜光凝治疗糖尿病视网膜病变与单纯全视网膜光凝治疗相比,能够更好地改善患者视力,减缓患者视网膜病变的发展,短期疗效好,临床应用前景广阔.
Clinical Study of Retinal Photocoagulation and Intravitreal Injection of Conbercept for Diabetes Retinopathy
Objective:To observe the efficacy of panretinal photocoagulation(PRP)and Compacercept intravitreal injection in the treatment of diabetic retinopathy(DR).Methods:the study time is set in May 2019 to May 2021,location in Linyi city central hospital,the study object for our hospital 100 patients with diabetic retinopathy,patients receive PRP treatment,according to random table is divided into test group(50 cases)and the control group(50 cases),the control group of patients only receive whole retinal photocoagulation(PRP)treatment,the test group again on the basis of whole retinal photocoagulation(PRP)injection.Data were compared for intraocular pressure,best corrected visual acuity,and macular foveal thickness before and after treatment and one month after treatment.Results:At 1 month after treatment,the corrected visual acuity was significantly better than the control group(P<0.001);the foveal thickness of the eyes and the control group(P<0.05);after treatment,not(P>0.05).Conclusion Conbercept intravitreal injection combined with panretinal photocoagulation can improve vision,slow down development of retinal lesions of patients,with better short-term effect than panretinal photocoagulation only,which has great clinical application prospects.

Panretinal photocoagulationConberceptBest corrected visionIntraocular pressureDiabetes retinopathy

朱万荣、贺作玉、杨帆

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临沂市中心医院,山东 临沂 276400

全视网膜光凝 康柏西普 最佳矫正视力 眼压 糖尿病视网膜病变

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(14)