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影响乳腺癌摆位误差的因素及干预对策

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目的 探究与分析影响乳腺癌摆位误差的因素以及干预对策。方法 选取2020年2月-2022年2月本院收治的110例接受放疗的乳腺癌患者纳入研究,按照患者的年龄进行分组,分别为>60岁组(n=61)及≤60岁组(n=49);按照不同的固定方式进行分组,分别为真空垫组(n=42)及乳腺托架联合热敷膜组(n=68);按照乳腺癌患侧的部分分为左侧组(n=64)及右侧组(n=46);按照不同手术切除方法分为保乳手术组(n=51)及切除手术组(n=59)。全部患者在接受调强治疗放射前,均接受了锥形束电子计算机断层扫描(CT),由此在每次治疗前获取正交图像数据,并将其与数字重建图像(DRR)进行配准,由此获得摆位误差,就此探讨并分析不同固定方式(真空垫、乳腺托架联合热敷膜)、手术方式(保乳手术、切除手术)、患侧(左侧、右侧)对摆位误差带来的影响,并分析其影响因素。结果 不同手术切除分组下,在3个轴方向上的摆位误差相比,差异无统计学意义(P>0。05)。在保乳术操作方式下,>60岁组在Y轴方向上的摆位误差与≤60岁组在Y轴方向上的摆位误差相比较高(P<0。05)。在其他相同手术方式下其他轴摆位误差上相比,差异无统计学意义(P>0。05)。在相同手术操作方式下,不同固定方式摆位误差相比,差异无统计学意义(P>0。05)。左侧乳腺癌患者在Y轴上的摆位误差与右侧乳腺癌患者在Y轴上的摆位误差相比较高,肿瘤位置对Y轴摆位误差的影响较为显著(P<0。05)。结论 乳腺癌患者在接受调强放疗时的乳腺患侧、手术方式以及固定方式等均能够对乳腺癌摆位误差带来影响,在实际临床工作中医生需要结合乳腺癌患者个体情况进行合理选择及搭配,由此保证减少摆位上的误差,从而达到提高放疗精确度的目的。
Influencing Factors and Intervention Strategies of Placement Error of Breast Cancer
Objective To explore and analyze influencing factors and intervention strategies of placement error of breast cancer.Methods The paper reviewed and analyzed clinical data of 110 patients with breast cancer with radiotherapy in radiotherapy department of Chifeng Hospital from February 2020 to February 2022,and divided them into>60 group(n=61)and≤ 60 group(n=49)according to age of patients.According to different fixation methods,patients were divided into vacuum pad group(n=42)and breast bracket combined with hot compress film group(n=68),and into left group(n=64)and right group(n=46)according to affected side of breast cancer,and into breast conserving surgery group(n=51)and resection surgery group(n=59)according to different surgical resection methods.All patients were treated with cone beam computed tomography(CT)before intensity modulated radiation therapy.Orthogonal image data were acquired before each treatment and matched with digital reconstructed images(DRR)to obtain placement errors.Based on this,the paper explored and analyzed influence of different fixation methods(vacuum pad,breast bracket combined with hot compress film),surgical methods(breast conserving surgery,resection surgery),and affected sides(left and right)on placement errors,and analyzed influencing factors.Results There was no statistically significant difference in placement errors in three axis directions among different surgical resection groups,(P>0.05).Under breast conserving procedure,placement error in Y-axis direction in>60 group was higher than≤ 60 group,difference was statistically significant,(P<0.05).There was no statistically significant difference in placement error of other axes under same surgical methods,(P>0.05).Under the same surgical procedure,there was no statistically significant difference in placement error between different fixation methods,(P>0.05).Placement error of left breast cancer patients on Y-axis was higher than right breast cancer patients on Y-axis.There was statistically significant for influence of tumor position on Y-axis placement error,(P<0.05).Conclusion Affected side of breast cancer,operation mode and fixation mode of breast cancer patients with intensity-modulated radiotherapy can have effect on placement error of breast cancer patients.During actual clinical practice,it is necessary to carry on reasonable selection and matching according to individual conditions of patients,to further reduce placement error of breast cancer patients,and improve accuracy of radiotherapy.

Breast cancerPlacement errorInfluencing factorsIntervention strategies

王晓磊、吴迪、贾昊男、董新然

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内蒙古自治区赤峰市医院放疗科,内蒙古 赤峰 024000

乳腺癌 摆位误差 影响因素 干预对策

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(14)