Clinical Application of Urapidil Injection in Treatment of Hypertension Emergencies
Objective To explore clinical application of urapidil injection in treatment of hypertension emergencies.Methods The paper chose 72 hypertensive emergency patients in our hospital from January 2021 to January 2023,and divided them into two groups according to medication method,urapidil injection group and nitroglycerin injection group,with 36 cases in each group.Statistical analysis of blood pressure,heart rate,heart,liver and kidney function indicators,life quality,clinical effect,incidence of adverse reactions,and symptom relief time was carried out between two groups.Results Diastolic blood pressure,systolic blood pressure,and heart rate in urapidil injection group was lower than nitroglycerin injection group(P<0.05),QOL-BRIEF scores were higher than nitroglycerin injection group(P<0.05).However,there was no significant difference in AST,ALT,GGT,SCr,and BUN levels between two groups(P>0.05).Total effective rate in urapidil injection group was higher than nitroglycerin injection group(P<0.05).Incidence of adverse reactions of patients with urapidil injection was lower than nitroglycerin injection group(P<0.05).There was no significant difference in relief time of chest tightness,chest pain,palpitations,dizziness,nausea,and dyspnea between two groups(P>0.05).Conclusion Urapidil injection can achieve better clinical application effect than nitroglycerin injection for hypertension emergencies,can effectively reduce blood pressure and heart rate,improve heart,liver and kidney function,life quality and clinical effect,reduce incidence of adverse reactions,and shorten symptom relief time of patients.
万方数据
维普
