首页|阿司匹林联合氯吡格雷治疗缺血性脑血管疾病的效果及安全性分析

阿司匹林联合氯吡格雷治疗缺血性脑血管疾病的效果及安全性分析

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目的 观察阿司匹林联合氯吡格雷治疗缺血性脑血管疾病的效果及安全性。方法 将2022年7月—2023年7月于本院接受治疗的60例缺血性脑血管疾病患者作为研究对象,将其应用摸球法分为对照组和观察组,每组30例。对照组采用阿司匹林治疗,观察组采用阿司匹林联合氯吡格雷治疗,比较两组的治疗效果。结果 观察组治疗总有效率比对照组组更高(P<0。05)。对比两组治疗前后认知功能、凝血功能指标,治疗前组间差异较小,治疗后MMSE各维度评分值均为观察组更高,凝血功能指标为观察组更具优势(P<0。05)。统计对比两组不良反应发生情况,观察组、对照组统计值分别为10。00%、6。67%,差异较小,组间用药安全性相当(P>0。05)。结论 在缺血性脑血管疾病患者中,行阿司匹林、氯吡格雷联合治疗效果显著,在促进患者认知功能及凝血功能指标改善方面具有良好效果,可以有效保证患者治疗安全性。
Effect and Safety Analysis of Aspirin Combined with Clopidogrel in Treatment of Ischemic Cerebrovascular Disease
Objective To observe effect and safety of aspirin combined with clopidogrel in treatment of ischemic cerebrovascular disease.Methods The paper chose 60 patients with ischemic cerebrovascular disease in our hospital from July 2027 to July 2023,and divided them into groups with touching ball method,and treated with different clinical treatment methods.Difference in nursing treatment was compared between groups.30 cases were included in both control group and observation group,corresponding nursing plans were aspirin treatment and clopidogrel treatment.Results Total effective rate of treatment in observation group was higher,with P<0.05.Cognitive function and coagulation function indicators were evaluated between two groups before and after treatment.There was little difference between groups before treatment,and the MMSE scores in all dimensions after treatment in observation group were higher.Coagulation function indicators had more advantages in observation group,with P<0.05.Incidence of adverse reactions between two groups was statistically analyzed.Difference in statistical values between observation group and control group was 10.00%and 6.67%respectively,which was relatively small.Safety of medication between the groups was comparable(P>0.05).Conclusion Combination therapy of aspirin and clopidogrel can achieve significant effect for patients with ischemic cerebrovascular disease,can improve cognitive function and coagulation function indicators of patients,and ensure safety of treatment effectively.

Ischemic cerebrovascular diseaseAspirinClopidogrelCurative effectCognitive functionCoagulation function indicatorsTreatment safety

刘向丽

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山东省临沂市沂南县中医医院,山东 临沂 276300

缺血性脑血管疾病 阿司匹林 氯吡格雷 疗效 认知功能 凝血功能指标 治疗安全性

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(16)