首页|急性脑梗死合并颈动脉粥样硬化患者颈动脉斑块的相关危险因素分析

急性脑梗死合并颈动脉粥样硬化患者颈动脉斑块的相关危险因素分析

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目的 探讨急性脑梗死患者并发颈动脉粥样硬化斑块的危险因素,为颈动脉粥样斑块疾病的临床预测和诊疗提供依据.方法 采用回顾性分析法,对天津市环湖医院在2021年11月—2023年6月收治的急性脑梗死患者共591例进行调查研究,对研究对象的临床资料和基础资料进行收集整理,参考研究对象颈动脉彩超结果,按是否有颈动脉斑块合并进行试验分组.其中,斑块组包含405例、非斑块组186例.为确保两组患者的脑梗死严重程度差异无统计学意义(P>0.05),将两组患者年龄、性别、吸烟史等基础资料以及血压、心率、尿酸、空腹血糖值等临床资料纳入单因素线性回归分析法中进行统计分析,对急性脑梗死患者并发颈动脉斑块的诱发因素进行探讨.结果 急性脑梗死患者并发颈动脉斑块的诱发因素包含空腹血糖值、尿酸值、吸烟史等.以危险程度作为排序依据,按照从低到高的顺序对其排序:尿酸(OR=1.007,P=0.006)、年龄(OR=1.1037,P<0.0001)、空腹血糖水平(OR=1.5361,P=0.0267)、吸烟史(OR=3.1131,P=0.0028).结论 在急性脑梗死合并颈动脉粥样硬化患者危险因素中,空腹血糖水平、年龄、尿酸值、吸烟史为独立危险因素.在临床治疗中,对于并发颈动脉斑块风险的控制,除需控制血脂水平外,尚且需要控制患者的血糖水平以及尿酸水平.
Risk Factors Analysis Related to Carotid Plaque of Acute Cerebral Infarction Patients with Carotid Atherosclerosis
Objective To explore risk factors of carotid atherosclerotic plaque of patients with acute cerebral infarction,and provide basis for clinical prediction,diagnosis and treatment of carotid atherosclerotic plaque disease.Methods The paper reviewed and analyzed 591 acute cerebral infarction patients with inpatient treatment at Tianjin Huanhu Hospital from November 2021 to June 2023 for investigation and study,collected and organized clinical and basic data of study subjects,and divided them into groups based on results of carotid artery ultrasound,whether there was carotid artery plaques merging.There were 405 cases in plaque group and 186 cases in non plaque group.There was no statistically significant difference in severity of cerebral infarction between two groups(P>0.05).Statistical analysis was carried out for basic data with univariate linear regression analysis method,including age,gender,smoking history,clinical data including blood pressure,heart rate,uric acid,and fasting blood glucose levels of two groups,to explore triggering factors of carotid artery plaques of patients with acute cerebral infarction.Results Triggering factors of carotid artery plaques of patients with acute cerebral infarction included fasting blood glucose levels,uric acid levels,smoking history,and etc.Degree of danger was seqenced in descending order,the results were:uric acid(OR=1.007,P=0.006),age(OR=1.1037,P<0.0001),fasting blood glucose level(OR=1.5361,P=0.0267),smoking history(OR=3.1131,P=0.0028).Conclusion Fasting blood glucose level,age,uric acid value and smoking history are independent risk factors of acute cerebral infarction with carotid atherosclerosis.During clinical treatment,it is necessary to control blood glucose and uric acid levels based on blood lipid level control to control risk of concurrent carotid artery plaques.

Acute cerebral infarctionCarotid atherosclerosisCarotid artery plaqueRisk factors

刘颖、王琴

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天津市环湖医院,天津 300350

急性脑梗死 颈动脉粥样硬化 颈动脉斑块 危险因素

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(16)
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