Effect Observation of Hypertonic Saline Solution for Severe Traumatic Brain Injury with Shock in Emergency Department
Objective To observe effect of hypertonic saline solution for severe traumatic brain injury with shock in emergency department and analyze effect of QOL scores.Methods The paper chose 104 patients diagnosed with severe traumatic brain injury and shock in emergency department of our hospital from June 2022 to June 2023 as research subjects,and divided them into observation group and control group based on parity of hospitalization numbers,with 52 cases in each group.Control group was treated with mannitol injection and Ringer's solution,while observation group with hypertonic saline solution.Clinical effect,vital signs,GCS scores,and QOL scores were compared between two groups.Results Clinical effective rate of observation group was significantly higher than control group,difference was statistically significant(P<0.05).Mortality rate of observation group was significantly lower than control group,difference was statistically significant(P<0.05).Compared with condition of 30 minutes after treatment,vital signs in observation group and control group were better after 2 hours of treatment.However,observation group had better RR,HR,ICP,CPP,MAP,and UPD than control group,(P<0.05).After treatment,observation group had higher GCS scores than control group(P<0.05).After treatment,observation group had higher QOL scores than control group(P<0.05).Conclusion Hypertonic saline solution can achieve high curative effect for severe traumatic brain injury with shock in emergency department,can improve success rate of rescue,accelerate recovery of patients,which has high clinical value.
Emergency severe traumatic brain injury with shockHigh osmotic salt solutionQOL scoresClinical effect