Objective To analyze clinical characteristics and prognostic risk factors of carbapenem resistant Pseudomonas aeruginosa(CRPA)infection patients.Methods The paper analyzed 131 hospitalized patients diagnosed with CRPA infection in Beijing Huairou Hospital from January 2018 to May 2023,and evaluated prognosis of fever with NLR values.Results Distribution of CRPA infection departments in death group was ICU mainly,while in survival group,distribution of CRPA infection departments was mainly respiratory department,neurosurgery,and ICU.Distribution of respiratory department,neurosurgery,and ICU showed statistical significance(P<0.05).Strains in death group had high resistance rate to piperacillin/tazobactam,ceftazidime,and cefepime,those in survival group had higher resistance rate to ciprofloxacin,levofloxacin,piperacillin/tazobactam,while piperacillin/tazobactam and cefepime showed statistical significance(P<0.05).Admission to ICU,concomitant Aspergillus infection,and CRPA bloodstream infection was independent risk factors for CRPA infection mortality(P<0.05).Conclusion Bloodstream infection,concurrent Aspergillus infection,and ICU admission of hospitalized patients with CRPA infection in our hospital is independent risk factors for high mortality.NLR value has some certain clinical application value in predicting prognosis of CRPA infection patients.
关键词
碳青霉烯类耐药铜绿假单胞菌/中性粒细胞与淋巴细胞比值/受试者工作特征曲线/危险因素
Key words
Carbapenem resistant Pseudomonas aeruginosa/Neutrophil to lymphocyte ratio/Receiver operating characteristic(ROC)curve/Risk factors
维普
万方数据