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新生儿高胆红素血症与缺血缺氧性心肌损害的关联性分析

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目的 探讨新生儿高胆红素血症与缺血缺氧性心肌损害的关联。方法 选取2022年7月—2023年7月本院收治的100例高胆红素血症患儿为研究对象,根据疾病进程分为心肌损害组(n=25)与无心肌损害组(n=75)。比较两组患儿性别、年龄胆红素水平及住院天数,Pearson相关性分析各指标与心肌损害发生的关系。结果 100例高胆红素血症患儿中出现心肌损害25例,发生率为25。00%。心肌损害组患儿血清胆红素水平及住院天数高于无心肌损害组,组间差异有统计学意义(P<0。05)。相关性分析显示,患儿住院天数及胆红素水平与心肌损害的发生呈正相关(P<0。05)。结论 高胆红素血症和新生儿心肌缺血缺氧有一定的关联,对于新生儿高胆红素血症的预防和治疗非常重要。及时发现和处理高胆红素血症,可以减少溶血现象,降低胆红素沉积对心肌的损伤。此外,新生儿心肌缺血缺氧需要及时诊断和治疗,以防止心肌损伤进一步加重。医务人员应密切关注新生儿的胆红素水平和心肌功能,针对性地进行干预,以保护患者心肌健康。
Correlation Analysis between Neonatal Hyperbilirubinemia and Ischemic Hypoxic Myocardial Damage
Objective To explore correlation between neonatal hyperbilirubinemia and ischemic hypoxic myocardial damage.Methods The paper chose 100 children with hyperbilirubinemia from July 2022 to July 2023 as study subjects,and divided them into myocardial injury group(n=25)and non myocardial injury group(n=75)according to the disease progression.Gender,age,bilirubin levels,and length of hospital stay were compared between two groups,Pearson correlation analysis on relationship was carried out between various indicators and incidence of myocardial damage.Results There were 25 cases of myocardial damage among 100 children with hyperbilirubinemia,with an incidence rate of 25.00%.Serum bilirubin levels and length of hospital stay in the group with myocardial injury were higher than the group without myocardial injury(P<0.05).Correlation analysis showed,length of hospital stay and bilirubin levels of patients were positively correlated with incidence of myocardial damage(P<0.05).Conclusion There is some certain correlation between hyperbilirubinemia and neonatal myocardial ischemia and hypoxia,which is crucial for prevention and treatment of neonatal hyperbilirubinemia.Timely detection and treatment of hyperbilirubinemia can reduce hemolysis and damage of bilirubin deposition to the myocardium.Moreover,neonatal myocardial ischemia and hypoxia should be timely diagnosed and treated to prevent further exacerbation of myocardial injury.Medical staff should closely monitor bilirubin levels and myocardial function of newborns,and intervene in a targeted manner to protect myocardial health.

NewborneHyperbilirubinemiaIschemic and hypoxic myocardial damageCorrelation analysis

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河源市源城区妇幼保健计划生育服务中心,广东 河源 517000

新生儿 高胆红素血症 缺血缺氧性心肌损害 关联性分析

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(17)