Clinical Effect Analysis of Smeglutide in Treatment of Obese Type 2 Diabetes
Objective To investigate clinical effect of smeglutide in treatment of obese type 2 diabetes.Methods The paper chose 100 obese patients with type 2 diabetes in our hospital from February 2022 to August 2023,and divided them into 50 cases in control group and 50 cases in experimental group randomly.The former was treated with metformin,while the latter with sitagliptin on the basis of the former.Blood glucose,lipid,body weight,SBP,DBP,TG,and TC indicators were observed and compared between two groups before and after intervention for 2 months.Results Fasting blood glucose before intervention,2-hour postprandial blood glucose,HbAlc,HOMA-IR,HOMA-β in both groups was compared,difference was not statistically significant(P>0.05).Experimental group had significantly lower fasting blood glucose,2-hour postprandial blood glucose,HbAlc,HOMA-IR,and significantly higher HOMA-β than control group,with statistically significant difference(P<0.05).After intervention,the BIM,SBP,DBP,TG,and TC of experimental group was significantly lower than control group,with statistical significance(P<0.05).Conclusion Smeglutide can achieve obvious hypoglycemic effect on type 2 diabetes patients,can improve weight,blood lipid and blood pressure indicators of patients.
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