Effect and Safety Observation of Entresto for Patients with Acute Myocardial Infarction and Heart Failure
Objective To explore effect and safety of Entresto for patients with acute myocardial infarction and heart failure.Methods The paper chose 98 patients with acute myocardial infarction and heart failure in our hospital from February 2021 to February 2023 for study,and divided them into experimental group and reference group evenly with blind touch dual color sphere method,with 49 cases in each group.Reference group was treated with routine treatment with enalapril,while experimental group with routine treatment with norxintal(sacubitril valsartan tablets).Levels of cardiac function,inflammatory factors,and incidence of adverse reactions were compared between two groups.Results LVESD,LVEDD,LVEF,and IVST levels in experimental group were better than control group(P<0.05).Levels of NT pro BNP,IL-6,IL-8,and TNF-a in experimental group were lower than control group(P<0.05).Comparison of adverse reactions between two groups was(P>0.05).Conclusion Entresto can improve cardiac function of patients with acute myocardial infarction combined with heart failure,reduce levels of inflammatory factors and incidence of adverse reactions,which has good curative effect and high safety.
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