Clinical Effect Evaluation of Combination Therapy of Thalidomide and Low-Dose Decitabine in Treatment of Myelodysplastic Syndrome
Objective To analyze clinical effect of thalidomide combined with low-dose dexamethasone in treatment of myelodysplastic syndrome.Methods The paper chose 90 patients with myelodysplastic syndrome in the hospital from January 2018 to December 2022 as study subjects,evaluated and compared total effective rate of treatment and blood count indicators comprehensively.Results Treatment effect in observation group was significantly better than control group in terms of complete response(CR)and overall response rate(ORR),with statistical significance(P<0.05).Post-treatment value in observation group was significantly higher than control group,difference was statistically significant,indicating treatment in observation group was significant better,(P<0.05).Conclusion Combination of thalidomide and low-dose dexamethasone has potential in improving survival and disease control rates of MDS patients.
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