首页|济川煎加减治疗脾肾阳虚型便秘疗效的Meta分析

济川煎加减治疗脾肾阳虚型便秘疗效的Meta分析

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目的 通过Meta分析评估济川煎治疗脾肾阳虚型便秘的临床疗效。方法 检索Cochrane Library、Pubmed数据库、CNKI数据库、维普数据库、万方数据库,收集济川煎治疗脾肾阳虚型便秘的随机对照试验,随即采用RevMan5。3软件对数据进行统计分析,并进行亚组分析及发表偏倚评估。结果 总共有10篇RCT文献纳入本研究,累计病例858例。Meta分析结果显示,济川煎治疗脾肾阳虚型便秘总有效率(RR=1。20,95%CI:1。14~1。27,P<0。00001)、痊愈率(RR=2。92,95%CI:2。05~4。16,P<0。00001)、粪便性状积分(MD=-0。36,95%CI:-0。39~-0。32,P<0。00001)、排便困难积分(MD=-0。34,95%CI:-0。37~-0。31,P<0。00001)、排便时间积分(MD=-0。4,95%CI:-0。45~-0。34,P<0。00001)、排便不尽感积分(MD=-0。34,95%CI:-0。36~-0。31,P<0。00001)均优于常规西药治疗。结论 济川煎治疗脾肾阳虚型便秘疗效确切,是临床上治疗便秘的有效方法。
Meta Analysis of Curative Effect of Modified Jichuan Decoction on Constipation of Spleen Kidney Yang Deficiency Type
Objective To evaluate clinical effect of Jichuan decoction in treatment of spleen kidney Yang deficiency type constipation based on meta-analysis.Methods The paper retrieved Cochrane Library,Pubmed database,CNKI database,VIP database,and Wanfang database to collect randomized controlled trials of Jichuan decoction in treatment of spleen kidney Yang deficiency type constipation.Data were statistically analyzed with RevMan5.3 software,and subgroup analysis and publication bias evaluation was carried out.Results The paper chose 10 RCT articles for study,with 858 cases.Meta-analysis showed total effective rate(RR=1.20,95%CI 1.14-1.27,P<0.00001),recovery(RR=2.92.95%CI 2.05~4.16,P<0.00001),fecal trait scores(MD=-0.36,95%CI-0.39~-0.32,P<0.00001),defecation difficulty scores(MD=-0.34,95%CI-0.37~-0.31,P<0.00001),defecation time scores(MD=-0.4,95%CI-0.45~-0.34,P<0.00001),and incomplete defecation scores(MD=-0.34,95%CI-0.36~-0.31,P<0.00001).Conclusion Jichuan decoction can achieve definite curative effect on spleen kidney Yang deficiency type constipation,which is an effective method for constipation in clinical practice.

Jichuan decoctionConstipationSpleen and kidney Yang deficiencyMeta analysis

薛晓梦、刘德武、肖子浩、龙景乾、卢鑫

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贵州中医药大学,贵州 贵阳 550002

贵州中医药大学第二附属医院,贵州 贵阳 550003

济川煎 便秘 脾肾阳虚 Meta分析

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(19)