济川煎加减治疗脾肾阳虚型便秘疗效的Meta分析
Meta Analysis of Curative Effect of Modified Jichuan Decoction on Constipation of Spleen Kidney Yang Deficiency Type
薛晓梦 1刘德武 2肖子浩 1龙景乾 1卢鑫1
作者信息
- 1. 贵州中医药大学,贵州 贵阳 550002
- 2. 贵州中医药大学第二附属医院,贵州 贵阳 550003
- 折叠
摘要
目的 通过Meta分析评估济川煎治疗脾肾阳虚型便秘的临床疗效.方法 检索Cochrane Library、Pubmed数据库、CNKI数据库、维普数据库、万方数据库,收集济川煎治疗脾肾阳虚型便秘的随机对照试验,随即采用RevMan5.3软件对数据进行统计分析,并进行亚组分析及发表偏倚评估.结果 总共有10篇RCT文献纳入本研究,累计病例858例.Meta分析结果显示,济川煎治疗脾肾阳虚型便秘总有效率(RR=1.20,95%CI:1.14～1.27,P<0.00001)、痊愈率(RR=2.92,95%CI:2.05～4.16,P<0.00001)、粪便性状积分(MD=-0.36,95%CI:-0.39～-0.32,P<0.00001)、排便困难积分(MD=-0.34,95%CI:-0.37～-0.31,P<0.00001)、排便时间积分(MD=-0.4,95%CI:-0.45～-0.34,P<0.00001)、排便不尽感积分(MD=-0.34,95%CI:-0.36～-0.31,P<0.00001)均优于常规西药治疗.结论 济川煎治疗脾肾阳虚型便秘疗效确切,是临床上治疗便秘的有效方法.
Abstract
Objective To evaluate clinical effect of Jichuan decoction in treatment of spleen kidney Yang deficiency type constipation based on meta-analysis.Methods The paper retrieved Cochrane Library,Pubmed database,CNKI database,VIP database,and Wanfang database to collect randomized controlled trials of Jichuan decoction in treatment of spleen kidney Yang deficiency type constipation.Data were statistically analyzed with RevMan5.3 software,and subgroup analysis and publication bias evaluation was carried out.Results The paper chose 10 RCT articles for study,with 858 cases.Meta-analysis showed total effective rate(RR=1.20,95%CI 1.14-1.27,P<0.00001),recovery(RR=2.92.95%CI 2.05～4.16,P<0.00001),fecal trait scores(MD=-0.36,95%CI-0.39～-0.32,P<0.00001),defecation difficulty scores(MD=-0.34,95%CI-0.37～-0.31,P<0.00001),defecation time scores(MD=-0.4,95%CI-0.45～-0.34,P<0.00001),and incomplete defecation scores(MD=-0.34,95%CI-0.36～-0.31,P<0.00001).Conclusion Jichuan decoction can achieve definite curative effect on spleen kidney Yang deficiency type constipation,which is an effective method for constipation in clinical practice.
关键词
济川煎/便秘/脾肾阳虚/Meta分析Key words
Jichuan decoction/Constipation/Spleen and kidney Yang deficiency/Meta analysis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据