Anesthesia Effect Exploration of Dexmedetomidine Combined with Etomidate Target Controlled Infusion for Endoscopic Retrograde Cholangiography of Elderly Patients
Objective To explore and analyze application value of dexmedetomidine combined with etomidate in the interventional treatment of stroke anesthesia. Methods This hospital 80 stroke patients in our hospital for interventional treatment and anesthesia from July 2021 to July 2023 into two groups according to sequence,the control group and the observation group,with 40 cases in each group,treated with etomidate anesthesia,dexmedetomidine combined with etomidate respectively. The postoperative spontaneous breathing recovery time,tracheal extubation time and wakefulness time,MAP and HR at different time points,APACHE Ⅱ scores and GCS scores after treatment,and incidence of adverse reactions were used as evaluation indicators of two groups. Results Postoperative spontaneous breathing recovery time,tracheal extubation time,and wakefulness time in the observation group was significantly shorter than the control group,difference was significant (P<0.05). The MAP and HR from T1 to T4 in the observation group were significantly lower than the control group,with statistical difference. There was no significant difference between two groups compared with compared with T0,P>0.05. After treatment,the APACHE Ⅱ scores and GCS scores in the observation group were significantly better than the control group,with significant difference (P<0.05). Incidence of adverse reactions in the observation group was 7.50％ (3/40),lower than 32.50％ (13/40) in the control group,with statistical difference,P<0.05. Conclusion Dexmedetomidine combined with etomidate can achieve significant application value in stroke intervention surgery,can control the adverse reactions,maintain breathing and circulation of patients effectively,which has significant safety and effectiveness.
万方数据
维普
