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首发精神分裂症的CT图像脑形态改变特征观察

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目的 观察分析首发精神分裂症患者的CT图像脑形态改变特征。方法 选取2021年3月—2022年6月本院收治的首发精神分裂症患者和同期在本院体检的健康者各100例作为研究对象,并分别将其归入实验组和对照组。两组研究对象均接受脑部CT检查,对比两组研究对象的侧脑室以及脑萎缩变化指标、脑沟扩大以及脑裂增宽指标、脑区差异和大脑左侧额叶CT值。结果 实验组患者的前角指数(FHI)、侧脑室脑比率(VBR)、侧脑室前角间最大宽度、透明隔-尾状核最大距离、左侧脑室颞角最大宽度和右侧脑室颞角最大宽度均大于对照组(P<0。05),前额叶萎缩指数(PFAI)、室中央指数(CMI)、侧脑室前角最大宽度和侧脑室前角间最小宽度均小于对照组(P<0。05)。实验组患者的外侧裂垂直部最宽距离(左侧)、外侧裂水平部最宽距离、额叶额上沟最宽距离和前纵裂池最大宽度均大于对照组(P<0。05),外侧裂垂直部最宽距离(右侧)小于对照组(P<0。05)。实验组患者的左侧中央旁小叶、左侧额极、左侧额上回、左侧扣带回峡部、右侧额上回、右内侧眶额叶和大脑左侧额叶CT值均小于对照组(P<0。05),右侧三角部CT值大于对照组(P<0。05)。结论 首发精神分裂症患者的CT图像脑形态改变特征为脑萎缩、脑体积减小以及脑室扩大,且其大脑左侧额叶CT值减低。
Observation of Characteristics of Brain Morphological Changes in CT Images of First-episode Schizophrenia
Objective To observe and analyze the characteristics of brain morphological changes in CT images of first-episode schizophrenia patients.Methods The start and end time points of the study were March 2021 and June 2022 respectively.During the period,the paper chose 100 patients with first-episode schizophrenia and 100 healthy individuals with physical examination as research subjects,included in the experimental group and the control group respectively.Both groups of study subjects were treated with brain CT scans,and lateral ventricles,indicators of brain atrophy,sulcus enlargement and fissure widening,difference in brain regions,and CT values of the left frontal lobe were compared between two groups.Results There was significant difference in indicators of lateral ventricle and brain atrophy,widening of sulci and fissures,changes in the third ventricle,difference in brain regions,and CT values of the left frontal lobe between two groups,(P<0.05).Conclusion Brain morphological changes characterized of first-episode schizophrenia patients in CT images is brain atrophy,decrease of brain volume,and enlarged ventricles.CT values of the left frontal lobe of the brain of first-episode schizophrenia patients decrease.

First-episode schizophreniaHealthy individuals with physical examinationsCT imageCharacteristics of brain morphology changes

王举

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阜宁县第三人民医院影像科,江苏 盐城 224400

首发精神分裂症 体检健康者 CT图像 脑形态改变特征

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(28)