Clinical Value Research of Cutoff Values of Various Indicators in Pulmonary Function Examination for Diagnosis and Effect Evaluation of COPD
Objective To explore the value of cutoff values of pulmonary function indicators in diagnosis and effect evaluation of chronic obstructive pulmonary disease (COPD). Methods The paper chose 81 COPD patients from January 2022 to March 2023 as the experimental group,and 80 patients with health examination during the same period as the control group. The first second forced expiratory volume (FEV1) and forced vital capacity (FVC) levels were detected in two groups with pulmonary function testing device,and the FEV1/FVC ratio was calculated. According to disease staging of the experimental group,patients were divided into acute exacerbation stage 25 cases and remission stage56 cases. Pulmonary function test results of each group and those in the experimental group at different stages were compared. Based on comparison of test results before and after treatment in the experimental group at different time,receiver operating characteristic (ROC) curve was drawn to evaluate value of pulmonary function indicators in diagnosis and effect evaluation of COPD,and obtaine cutoff values and sensitivity indicators. Results The levels of FEV1,FVC,and FEV1/FVC in the experimental group were lower than the control group (P＜0.05). The levels of FEV1 and FVC of COPD patients with acute exacerbation were lower than those with remission (P＜0.05),there was no statistically significant difference in FEV1/FVC results between acute exacerbation and remission (P＞0.05). The FEV1,FVC,and FEV1/FVC in the experimental group were higher 2 weeks and 1 month after treatment than before (P＜0.05). Under the ROC curve,indicators of FEV1 (cut-off value of 1.25L,sensitivity of 88.25％),FVC (cut-off value of 1.77L,sensitivity of 90.12％),and FEV1/FVC (cut-off value of 60.15％,sensitivity of 93.25％) showed high diagnostic effect. Conclusion Cutoff value of pulmonary function indicators can be reference for diagnosis and effect evaluation of COPD,with good diagnostic value.
Chronic obstructive pulmonary diseasePulmonary function testCutoff valueDiagnosisEffect evaluation
万方数据
维普
