Correlation between grip strength promotion and improvement of body composition and metabolic disorders in health examination population of different genders
Objective To explore the correlation between grip strength promotion and improvement of body composition and metabolic disorders in health examination population of different genders.Methods In this retrospective cohort study,clinical data of 600 people who received health examination and grip strength check-up two times or more in the Medical Examination Center of Peking University Third Hospital from January 2018 to November 2022 were selected.The general data,physical examination,biochemical parameters,body composition and grip strength results were collected.After the first physical examination,the grip strength test was conducted,appropriate resistance strength exercises were given based on individual evaluation results.A health lecture was held,and the information related to health exercise was pushed through WeChat official account every week.The grip strength test was completed at the same time at the second physical examination,and the difference between the two test results was calculated before and after the second physical examination.The generalized estimation equation was used to analyze the correlation between the improvement of grip strength and the improvement of body composition and metabolic disorders in different gender health-check population.Results In man and women,the body mass index[(25.50±3.66)vs(25.33±3.74)kg/m2,(22.41±3.55)vs(22.25± 3.46)kg/m2]and grip strength[(42.71±7.30)vs(41.77±7.36)kg,(25.28±5.30)vs(23.98±4.87)kg]at the second health check-up were all significantly higher than those at the first time,and the diastolic blood pressure[(72.79±10.30)vs(74.47±9.85)mmHg(1 mmHg=0.133 kPa),(66.93±8.90)vs(68.92±9.42)mmHg]and serum homocysteine[(17.96±14.09)vs(19.27±14.26)pmol/L,(9.47± 3.91)vs(10.26±3.90)pmol/L]were all significantly lower than those at the first time(all P＜0.05).Among man,the low-density lipoprotein cholesterol(LDL-C)at the second physical examination was significantly lower than that at the first time[(2.94±0.78)vs(3.00±0.69)mmol/L](all P＜0.05).Among women,the systolic blood pressure and uric acid at the second health check-up were both significantly lower than those at the first time[(109.34±12.85)vs(110.54±12.32)mmHg,(276.91± 62.46)vs(287.16±68.78)pmol/L],and the waist-hip ratio was significant higher(85.8％±5.1％vs 85.4％±5.0％)(all P＜0.05).In males,the decreased aspartate aminotransferase(OR=0.932,95％CI:0.888-0.978)and the increased skeletal muscle index(OR=75.370,95％CI:29.012-195.806)were both positively correlated with the elevation of grip strength(all P＜0.05);and in females,the decreased homocysteine(OR=0.876,95％CI:0.782-0.982)and glycosylated hemoglobin(OR=0.423,95％CI:0.222-0.805)and increased skeletal muscle index(OR=22.918,95％CI:11.114-47.256)were all positively correlated with the elevation of grip strength(all P＜0.05).Conclusion There is a positive correlation between the improvement of grip strength and the improvement trend of body composition and metabolic disorders in in health examination population of different genders.
Physical examinationGrip strengthBody compositionMetabolicSkeletal muscle index
万方数据
维普
