Multiple correspondence analysis of the detection and risk factors of non-alcoholic fatty liver disease in middle-aged and young adult population undergoing physical examination
Objective To analyze the detection of non-alcoholic fatty liver disease(NAFLD)and the multiple corresponding relationships of its risk factors in a middle-aged and young adult population undergoing health check-ups.Methods This study was a cross-sectional study conducted on 15 423 individuals aged between 18 and 59 who underwent health check-ups at the Health Management Center of Henan Provincial Hospital of Traditional Chinese Medicine from January to December 2021.Relevant health examination data was collected,including basic information(age,gender,past medical history,smoking and alcohol consumption),physical examination,laboratory indicators such as blood lipids and blood glucose,and abdominal ultrasound results.The chi-square test was used to compare the prevalence of NAFLD among different characteristics of the population,and multiple correspondence analysis was employed for statistical analysis of related influencing factors.Results A total of 5 859 cases of NAFLD were detected in this study,with a detection rate of 37.99％.The detection rate of NAFLD gradually increased with age(x2=828.841,P＜0.001)and body mass index(BMI)(x2=1 889.809,P＜0.001).The detection rates of NAFLD were higher in individuals with hypertension,diabetes,hypercholesterolemia,hypertriglyceridemia,low high-density lipoprotein cholesterolemia,high low-density lipoprotein cholesterolemia,and hyperuricemia compared to those without these conditions(x2 value was 1 223.673,364.808,444.074,2 436.765,1 323.736,591.478,and 943.069,respectively,all P＜0.001).Multiple correspondence analysis revealed that NAFLD was closely related to hypertension,hypertriglyceridemia,diabetes,hyperuricemia,overweight,obesity,and the age group of 45-49 years.Correspondence analysis graphs for males and females showed associations between NAFLD and hypertension,hypertriglyceridemia,hyperuricemia,overweight,and obesity.In males,NAFLD was closely related to the age group of 35-49 years,while in females,it was closely associated with the age group of 45-49 years and diabetes.Conclusions The detection rate of non-alcoholic fatty liver disease is relatively high in middle-aged and young adult populations.Males,those who are overweight or obese,and individuals with hypertension,diabetes,hyperuricemia,or abnormal blood lipids are more susceptible to non-alcoholic fatty liver disease.
万方数据
维普
