Objective To search and obtain the best evidence for non-pharmacological anticoagulant intervention for preventing clotting of extracorporeal circuits during CRRT.Methods We searched databases(UpToDate,PubMed,Cochrane Library,CNKI,Wanfang database,etc)to collect relevant clinical evidences related to non-pharmacological anticoagulant intervention for preventing clotting of extracorporeal circuits during CRRT.The retrieval time was from the establishment of the database to July 31,2023.Two investigators independently screened the literature,evaluated the quality of the literatures,extracted and integrated the evidence.Results A total of 16 articles were included in this study,including 4 guidelines,6 systematic reviews,3 expert consensuses,and 3 expert opinions.A total of 23 best evidences were summarized from 5 aspects,including team factors,vascular access factors,machine factors,operation-related factors,and patient factors.Conclusion This study summarizes the best evidence of non-pharmacological anticoagulant intervention for preventing clotting of extracorporeal circuits during CRRT,and provides evidence-based basis for standardizing nurses'CRRT nursing behavior for critically ill patients,and further improves the sufficiency of CRRT for critically ill patients.
维普
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