摘要
肌少症是一种以肌肉数量、质量、力量逐渐减退为特征的疾病,目前已受到广泛关注.老年脑卒中患者后期极易发生肌少症,脑卒中和肌少症在发病机制上密切相关,二者在疾病进展过程中相互影响.既往研究发现,肌少症与老年脑卒中患者病变的严重程度、不良功能结果、神经功能恶化、复发性脑血管事件、认知功能障碍均有一定的关系.本文就肌少症对老年脑卒中患者预后影响的研究现状进行综述,并探讨二者之间的关系,为日后临床研究提供方向.
Abstract
Sarcopenia,a disease characterized by the gradual loss of muscle quantity,mass and strength,has become a wide concern.Sarcopenia occurs easily in the elderly patients with late-stage stroke.Stroke and sarcopenia are closely associated with patho-genesis,and the two affect mutually in the disease progression.Previous studies have found a relationship between sarcopenia and the severity of lesions,adverse functional outcomes,neurological deterioration,recurrent cerebrovascular events,and cognitive dysfunction in the elderly stroke patients.In this article,we reviewed the current research status of the influence of sarcopenia on the prognosis of the elderly stroke patients and discussed the correlation between the two,so as to provide directions for future clinical research.