中华老年多器官疾病杂志2024,Vol.23Issue(4) :316-320.DOI:10.11915/j.issn.1671-5403.2024.04.068

呼吸机引起的膈肌功能障碍与脱机肺水肿的研究进展

Progress in research of ventilator-induced diaphragm dysfunction and weaning-induced pulmonary oedema

姜辉 刘丽梅
中华老年多器官疾病杂志2024,Vol.23Issue(4) :316-320.DOI:10.11915/j.issn.1671-5403.2024.04.068

呼吸机引起的膈肌功能障碍与脱机肺水肿的研究进展

Progress in research of ventilator-induced diaphragm dysfunction and weaning-induced pulmonary oedema

姜辉 1刘丽梅1
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作者信息

  • 1. 中部战区总医院干部病房,武汉 430070
  • 折叠

摘要

膈肌功能障碍和脱机引起的肺水肿是导致脱机失败的两个重要原因.膈肌功能障碍会降低膈肌收缩力量,使肺通气减少,引起脱机失败;脱机时胸内负压增大,通过增加静脉回流和左心室后负荷,导致脱机肺水肿和呼吸窘迫.本文对膈肌功能障碍和脱机引起的肺水肿的发生机制、诊断方法以及治疗策略进行综述.

Abstract

Diaphragm dysfunction and weaning-induced pulmonary oedema are two important causes of weaning failure.Diaphragm dysfunction can reduce contraction force of the diaphragm,compromising pulmonary ventilation loss and causing a subsequent weaning failure.Large negative swings in intrathoracic pressure during weaning tend to increase the venous return and the left ventricular after-load,contributing to weaning-induced pulmonary oedema and respiratory distress.This article reviews the mechanisms,diagnosis and strategies of treatment of diaphragm dysfunction and weaning-induced pulmonary oedema.

关键词

膈肌/肺水肿/肺超声/脱机困难

Key words

diaphragm/pulmonary edema/lung ultrasound/difficult weaning

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基金项目

湖北省卫生健康委科研联合项目(WJ2019H112)

出版年

2024
中华老年多器官疾病杂志
中国人民解放军总医院老年心血管病研究所

中华老年多器官疾病杂志

CSTPCD
影响因子:0.728
ISSN:1671-5403
参考文献量52
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