Clinical efficacy of balloon stent kissing technique and jailed wire technique in treatment of coronary bifurcation lesions in the elderly
Objective To investigate the clinical efficacy of interventional therapy with balloon stent kissing technique(BSKT)and jailed wire technique(JWT)for coronary bifurcation lesions(CBL)in the elderly.Methods A retrospective analysis was conducted on 124 elderly CBL patients treated in our hospital from August 2019 to April 2021.Their clinical data were collected and analyzed,and those receiving JWT interventional therapy were assigned into the control group(n=64),while those undergoing BSKT interventional therapy were included in the observation group(n=60).SPSS statistics 20.0 was used for data analysis,student's t test was employed for intergroup comparison.Results In 6 months after operation,the minimum lumen diameter(MLD)of the main vessel was increased,and the stenosis,diameter stenosis rate(DS)and lesion length were decreased in both groups(P<0.05),but there were no significant differences in the above four indicators between the two groups(P>0.05).For the branch vessels,the MLD was increased,and the stenosis,DS and lesion length were decreased in 6 months after surgery in both groups(P<0.05).The MLD of branch vessels was significantly higher,and the stenosis,DS and lesion length were lower in the observation group than the control group(P<0.05).In 72 h after surgery,the levels of high-sensitivity cardiac troponin I(hs-cTnI),high-sensitivity C-reactive protein(hs-CRP)and lipoprotein-associated phospholipase A2(LP-PLA2)were significantly lower,while those of angiotensin Ⅱ(AngⅡ)and von Willebrand factor(vWF)were significantly lower in observation group than the control group(P<0.05).Conclusion BSKT inter-ventional therapy is superior to JWT in treatment of CBL in the elderly patients,with the advantages of effectively reducing the myocardial function injury and endothelial function injury,and exerting a good protective effect on branch blood vessels,and therefore,it is worthy of promotion in clinical practice.