糖尿病患者认知衰弱的研究进展
Research progress of cognitive frailty in elderly patients with diabetes mellitus
梁财 1陶娅 2蒲凤 1林静 1孙唯佳 1周云3
作者信息
- 1. 川北医学院临床医学院,四川 南充 637000
- 2. 四川绵阳四〇四医院 内分泌代谢科,四川 绵阳 621000
- 3. 四川绵阳四〇四医院 全科医学科,四川 绵阳 621000
- 折叠
摘要
胰岛素抵抗是老年 2 型糖尿病患者认知衰弱的重要病理生理机制,及早识别相关危险因素并进行干预,对改善患者生活质量具有重要意义.甘油三酯葡萄糖指数作为一种新型的胰岛素抵抗指数,也可增加老年2 型糖尿病患者认知衰弱的风险.本文旨在综述胰岛素抵抗在老年2 型糖尿病患者认知衰弱发病机制中的研究进展,及其与认知衰弱危险因素之间的相关性;同时,本文还探讨甘油三酯葡萄糖指数与认知衰弱相关性的研究进展,以期为减缓2 型糖尿病患者认知衰弱进展提供有益参考.
Abstract
Insulin resistance is an important pathophysiological mechanism of cognitive frailty(CF)in elderly patients with type 2 diabetes mellitus(T2DM),and early identification of its relevant risk factors and implementation of interventions are of great impor-tance for improving their quality of life.Triglyceride-glucose(TyG)index,as a new marker of insulin resistance index,can also increase the risk of CF in elderly T2DM patients.In this article,we reviewed the research progress of insulin resistance in the pathogenesis of CF and its correlation with related risk factors of CF.We also explored the research progress on the correlation between TyG index and CF in order to provide useful references for slowing the progression of CF in patients with T2DM.
关键词
胰岛素抵抗/2型糖尿病/认知衰弱/甘油三酯葡萄糖指数Key words
insulin resistance/type 2 diabetes mellitus/cognitive frailty/triglyceride-glucose index引用本文复制引用
基金项目
绵阳市卫健委 2022年科研课题鼓励项目(202220)
出版年
2024
NETL
NSTL
万方数据