首页|钠-葡萄糖共转运蛋白2抑制剂在老年2型糖尿病合并常见心血管疾病中的应用进展

钠-葡萄糖共转运蛋白2抑制剂在老年2型糖尿病合并常见心血管疾病中的应用进展

扫码查看
老年2型糖尿病(T2DM)患者常有多病共存现象,而合并心血管疾病(CVD)最为常见,是其致残、致死的首要原因.钠-葡萄糖共转运蛋白2抑制剂(SGLT2i)是一种新型降糖药物,其心血管保护作用受到广泛关注,在老年T2DM与CVD共病的治疗上展现出良好的前景.本文就SGLT2i在T2DM合并心力衰竭、高血压、动脉粥样硬化、心肌梗死等常见CVD中的应用研究进展作一综述.
Advances in application of sodium-glucose co-transporter 2 inhibitor in elderly type 2 diabetes mellitus patients with concomitant common cardiovascular diseases
Elderly patients with type 2 diabetes mellitus(T2DM)often have multiple coexisting diseases,and the complication of cardiovascular diseases(CVD)is the most common,which is the primary cause of disability and death.Sodium-glucose co-transporter protein 2 inhibitor(SGLT2i)is a novel hypoglycemic agent,which has received widespread attention for its cardio-protective effects,and shows good prospects for the treatment of co-morbidities of T2DM and CVD in the elderly.In this article,we reviewed the progress of SGLT2i in T2DM combined with heart failure,hypertension,atherosclerosis,myocardial infarction and other common CVD.

diabetes mellitus,type 2sodium-glucose co-transporter protein 2 inhibitorgeriatric co-morbiditiescardiovascular diseasesheart failure

张辉、李泱、刘传斌

展开 >

中国人民解放军总医院京西医疗区,北京 100144

中国人民解放军总医院第六医学中心心血管病学部,北京 100048

糖尿病,2型 钠-葡萄糖共转运蛋白2抑制剂 老年共病 心血管疾病 心力衰竭

国家自然科学基金国家自然科学基金

8220036682370327

2024

中华老年多器官疾病杂志
中国人民解放军总医院老年心血管病研究所

中华老年多器官疾病杂志

CSTPCD
影响因子:0.728
ISSN:1671-5403
年,卷(期):2024.23(8)
  • 3