摘要
肌少症是一组与年龄相关的综合征,通常以骨骼肌含量减少、肌力下降和功能减低为特征,可导致老年人跌倒、衰弱、失能甚至死亡等一系列不良结局,给卫生保健系统带来沉重的负担.目前尚无治疗肌少症的特效药物,主要通过运动干预预防和治疗肌少症.本文就肌少症患者的运动干预病理生理学机制及推荐老年人运动干预的形式、强度和频次等内容进行综述,为临床实践中对肌少症的预防和治疗提供指导.
Abstract
Sarcopenia is a group of syndromes characterized by age-related declines in skeletal muscle mass,strength,and func-tion,which leads to a series of adverse outcomes such as falls,frailty,disability,and even death in the elderly.It also poses a signifi-cant burden on healthcare systems.Currently,there is no specific medication for sarcopenia,and exercise intervention is mainly used for its prevention and treatment.In this article,we reviewed the pathophysiological mechanism of exercise intervention and the recom-mendations for forms,intensity,and frequency of exercise for the elderly with sarcopenia in order to provide guidance for its prevention and treatment in clinical practice.