摘要
膝关节炎是影响老年人活动与参与的常见疾病，目前临床上对其诊断与随访主要依赖X线和Kellgren/Lawrence（K/L）分级，缺少生物力学维度的随访与科研，较难预测膝关节炎的进展和功能改变。本文通过综述基于X线距离和角度测量、基于X线图像处理和基于生物力学参数的各生物力学标志物对膝关节炎进展预测的贡献，说明生物力学标志物对预测膝关节炎进展的有效性和当前的局限性，为进一步进行相关研究提供帮助。
Abstract
Knee osteoarthritis is a common disease that affects the activities and participation of the elderly. At present, its clinical diagnosis and follow-up mainly rely on X-ray and Kellgren/Lawrence (K/L) grade, and lack of follow-up and scientific research of biomechanical dimensions, which is difficult to predict the progression and functional changes of knee osteoarthritis. The paper reviewed contribution of the distance and angle measurement based on X-ray, X-ray image processing and the biomechanical markers based on biomechanical parameters for prediction of knee osteoarthritis progress. To show the biomechanical markers' effectiveness and limitations to predict knee osteoarthritis progress and effectiveness of the current limitations and help for further research.
基金项目
国家科技部重点研发计划项目(2020YFB1711500)
国家自然科学基金(82072412)
上海市科委项目(19441917500)
上海市科委项目(19441908700)
上海交通大学医学院附属第九人民医院临床研究型MDT项目(201914)
上海市科委项目(22015820100)
上海交通大学医学院附属第九人民医院教学培育项目(JYJX03202103)
万方数据