The predictive value of sarcopenia index for postoperative pneumonia in ≥ 70 years old patients of esophageal cancer
Objective To investigate the clinical application value of commonly used preoperative indicators of sarcopenia in predicting postoperative pneumonia in patients aged 70 years and above with esophageal cancer.Methods A retrospective analysis was conducted on the clinical data of 398 elderly patients(≥70 years old)with esophageal squamous cell carcinoma who underwent thoracic laparoscopic radical resection of esophageal cancer in our hospital from January 2020 to December 2021.The study aimed to investigate the correlation between clinical pathological indicators and commonly used measurement indicators of sarcopenia and postoperative pneumonia.Statistical analysis was performed to analyze the data.Results The study found that the proportion of postoperative pneumonia in esophageal squamous cell carcinoma patients aged 70 years and above was 27.9％(111 out of 398).The pneumonia group had significantly lower preoperative BMI and peak expiratory flow(PEF)measurements compared to the non-pneumonia group,with statistically significant differences(t=2.799,2.674,both P＜0.05).Logistic multivariate analysis revealed that low PEF,low psoas major muscle index(PMI),and low psoas muscle density(PMD)were the primary risk factors for postoperative pneumonia in esophageal cancer patients aged 70 years and above(Wald x2 values were 7.577,6.091,6.845,all P＜0.05).The risk of postoperative pneumonia in esophageal cancer patients aged 70 years and above with low PEF,low PMI,and low PMD was found to be 1.969 times higher(95％CI:1.215-3.185,P=0.006),1.912 times higher(95％CI:1.143-3.205,P=0.014),and 1.832 times higher(95％CI:1.164-2.882,P=0.009)respectively,compared to patients with high PEF,high PMI,and high PMD.Conclusions Low PEF,low PMI,and low PMD are significant risk factors for postoperative pneumonia in esophageal cancer patients aged 70 years and older.Preoperative PEF,PMI,and PMD,which are commonly utilized measurement indicators for sarcopenia,can be utilized as early screening indicators for postoperative pneumonia.
NETL
NSTL
万方数据
维普
