Objective To examine the influence of handgrip strength(HGS)on the intrinsic capacity(IC)and explore the correlation between HGS and intrinsic capacity subdomains in elderly patients of varying genders.Methods A cross-sectional study was conducted on 201 inpatients admitted to the Geriatric Department of Zhejiang Hospital from May 2020 to November 2021.The study collected data on the patients'general situation and intrinsic capacity assessment,which included physical function,nutritional status,visual and hearing status,cognitive function,and depressive mood.The patients were grouped based on the number of impaired subdomains of intrinsic capacity.Multivariate ordered Logistic regression analysis was performed to identify the factors influencing the impaired subdomains of intrinsic capacity.The patients were further divided into normal and decreased grip strength groups based on HGS thresholds of less than 26 kg for males and less than 18 kg for females.Binary Logistic regression analysis was then used to investigate the relationship between HGS and the different subdomains of intrinsic capacity among males and females.Results Among the 201 inpatients,68 were impaired in 0 to 1 subdomain(33.8％),103 in 2 to 3 subdomains(51.2％),and 30 in more than 3 subdomains(14.9％).After adjusting for confounding factors using multivariate ordered Logistic regression analysis,the HGS of the 2 to 3 and more than 3 subdomain groups were found to be lower than the 0 to 1 subdomain group(OR=0.957,95％CI:0.924-0.993,P=0.019).Among the patients,117(58.2％)had normal HGS,while 84(41.8％)had decreased HGS.In the binary Logistic regression analysis of older adults,adjusted for confounders,the results indicated that older men with decreased HGS had higher odds of experiencing cognition problems(OR=3.919,95％CI:1.301-11.804,P=0.015).Similarly,older women with decreased HGS had higher odds of having locomotion(OR=10.623,95％CI:2.374-47.536,P=0.002),vitality(OR=7.386,95％CI:1.875-29.095,P=0.004),and cognition(OR=4.835,95％CI:1.218-19.196,P=0.025)problems.Conclusions The key population for intrinsic capacity screening should be elderly patients with decreased HGS.It is important to note that there are differences in the subdomains of impaired intrinsic capacity among elderly individuals with decreased HGS of different genders.As a result,it is crucial to prioritize the development of intervention programs to improve intrinsic capacity based on the specific needs of elderly individuals of different genders.
维普
万方数据