Study on the diagnostic value and safety of endobronchial ultrasound-guided transbronchial needle aspiration in elderly patients with hilar and/or mediastinal masses
Objective To assess the diagnostic value and safety of endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)in elderly patients with hilar and/or mediastinal masses.Methods This study retrospectively analyzed the clinical data of patients with hilar and/or mediastinal lymphadenopathy who underwent EBUS-TBNA examination at the Department of Respiratory and Critical Care Medicine of Beijing Hospital from June 2015 to March 2023.The study compared and analyzed the general situation,puncture surgery,and postoperative pathological results of patients aged 18-64 and over 65.Furthermore,it summarized the diagnostic value and safety of EBUS-TBNA.Results The study included a total of 362 patients.The researchers performed a total of 522 punctures on groups of lymph nodes and 87 punctures on groups of hilar/mediastinal masses.On average,there were(5.1±1.9)EBUS-TBNA punctures per point.The average operating time was(20.1±1.8)minutes.There was no significant difference in the number of puncture needles used between the 18-64 year-old group and the≥65 year-old group(x2=0.707,P=0.699).Additionally,there was no statistically significant difference in the incidence of complications between the two groups[9.2％(14/152)vs.9.5％(20/210),x2=0.010,P=0.920].In the study,a total of 227 cases(62.7％)of malignant lesions and 126 cases(34.8％)of benign lesions were confirmed through EBUS-TBNA examination in 362 patients.Additionally,9 cases(2.5％)of patients were diagnosed with malignant tumors after undergoing percutaneous lung puncture or surgery.The sensitivity of EBUS-TBNA in diagnosing malignant lesions in the hilar and/or mediastinum was found to be 96.2％(227/236),with a specificity of 100.0％(126/126).Furthermore,the diagnostic sensitivity of EBUS-TBNA was 95.1％(78/82)in the 18-64 year-old group and 96.6％(140/145)in the≥65 year-old group.Importantly,there was no statistically significant difference in EBUS-TBNA diagnostic sensitivity between the two patient groups(x2=0.281,P=0.596).Conclusions In patients aged ≥65 years undergoing EBUS-TBNA procedures,there is no difference in the incidence of complications compared to patients aged 18-64 years.EBUS-TBNA serves as a crucial diagnostic tool for elderly patients with hilar and/or mediastinal masses,enabling them to obtain pathology results and receive appropriate further treatment.
NETL
NSTL
万方数据
