Aging has become an increasingly important topic in the field of geriatrics,with the exploration of aging-related biomarkers providing a foundation for interventions aimed at delaying and reversing aging.Over the years,numerous biomarkers have been developed at both the cellular level(aging mechanisms,histology)and individual level(composite biomarkers,functional biomarkers).This article systematically discusses the characteristics and application scenarios of significant biomarkers at these two levels,and also outlines comparative studies conducted on aging biomarkers.Future research should consider synthesizing multidimensional aging biomarkers at all levels to achieve a more accurate and reliable assessment of aging.Furthermore,there is great potential for further exploration of aging biomarkers through the analysis of histologic data.
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