Clinical and imaging features of isolated infarction of the splenium of the corpus callosum and reversible splenial lesion syndrome
Objective To compare the clinical characteristics and magnetic resonance imaging(MRI)features of isolated infarction of the splenium of the corpus callosum and reversible splenial lesion syndrome(RESLES).Methods Clinical and imaging findings of 12 patients with a clinical diagnosis of isolated infarction of splenium of the corpus callosum and 13 patients with RESLES from Deportment of Neurology in Beijing Geriatric Hospital between December 2018 and November 2022 and follow-up results were retrospectively analyzed.Results The patients with isolated infarction of SCC were older than the patients with RESLES(age of patients with isolated infarction of SCC:67.6±9.2,age of patients with RESLES:23.2±17.8).All patients with infarction had one to three risk factors for cerebrovascular diseases.Both two groups showed hyperintense lesions on T2WI,fluid-attenuated inversion recovery(FLAIR)and diffusion-weighted imaging(DWI),and hyperintense lesions on T1WI and a low apparent diffusion coefficient(ADC).Most SCC infarctions occurred unilaterally(one case with bilateral lesions and 12 cases with unilateral lesions),with irregular dot-like or patchy lesions.Nine patients in the infarction group completed the follow-up,during which the lesions did not disappear on the T1WI,T2WI,FLAIR and ADC sequence.One patient in this group had a recurrent stroke.In the RESLES group,all lesions were located on the midline of SCC,with round,oval or boomerang-shaped lesions.All patients in the RESLES group completed the follow-up,during which lesions either shrank or disappeared.Conclusions Infarction and RESLES can both result in SCC lesions.The existence of risk factors and imaging features about the locations of lesions,the morphology,and lesion changes during follow-up are helpful in the differential diagnosis.
Corpus callosumIsolated infarction of the splenium of the corpus callosumReversible splenial lesion syndromeMagnetic resonance imaging
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