功能性近红外光谱脑成像技术在轻度认知障碍诊疗中的应用进展
Usage of functional near-infrared spectroscopy in diagnosis and treatment of mild cognitive impairment
濮正平 1黄虹娜 2崔东红2
作者信息
- 1. 嘉兴学院附属精神卫生中心(嘉兴市康慈医院)老年精神科,嘉兴 314500;上海交通大学附属精神卫生中心上海市重性精神病重点实验室,上海 201108
- 2. 上海交通大学附属精神卫生中心上海市重性精神病重点实验室,上海 201108
- 折叠
摘要
轻度认知障碍(MCI)进展为痴呆的风险较高,目前仍然缺乏准确度高、适宜推广的MCI筛查技术.近年来的研究显示,功能性近红外光谱(fNIRS)技术具有筛查MCI的潜力,且可用于干预措施的疗效评估.本文从概念背景、认知功能评估的运用、MCI诊断与筛查、疗效评估、存在的不足等角度综述了 fNIRS在MCI诊疗方面的运用与前景,以期为后续的临床研究与转化提供思路与参考.
Abstract
Mild cognitive impairment(MCI)carries a high risk of progressing to dementia,yet there is a lack of specific and accurate screening techniques.Recent research suggests that functional near-infrared spectroscopy(fNIRS)holds significant potential for screening MCI and evaluating the effectiveness of therapeutic interventions.Therefore,this paper aims to review the application and future prospects of fNIRS in diagnosing and treating MCI.The review covered various aspects including the background,assessment of cognitive function,screening methods for MCI,evaluation of therapeutic efficacy,and limitations.The findings of this review can serve as a valuable reference for future clinical studies.
关键词
功能性近红外光谱/轻度认知障碍/认知功能Key words
Functional near-infrared spectroscopy/Mild cognitive impairment/Cognitive function引用本文复制引用
基金项目
国家重点研发计划(2017YFC0909200)
浙江省医药卫生科技计划(2023XY053)
浙江省中医药科技计划(2023ZL703)
出版年
2024
NETL
NSTL
万方数据