Mechanism of iron death regulation in sarcopenia and therapeutic research
Sarcopenia is a common geriatric disease with increasing incidence year by year,the harm is great,nutritional support is not good.Iron death is a novel type of cell death,characterized by abnormal iron metabolism,lipid peroxidation and an abnormal increase in reactive oxygen species.Some studies have shown that iron death is in part related to the occurrence of sarcopenia,and iron death will hinder muscle regeneration and repair,leading to muscle loss.Studies have shown that the modulation of cellular iron death of sarcopenia is effective in increasing muscle mass and strength and improving physical function.In this paper,we summaried the latest research on the mechanism of action and treatment of regulating iron death to prevent and treat sarcopenia,with a view to providing a reference for the clinical prevention and treatment of sarcopenia.
万方数据
维普
