Research progress of Alzheimer's disease with visual impairment
Alzheimer's disease(AD)is the most common cognitive disorder characterized by progressive cognitive decline,neuropsychiatric symptoms,and impaired multiple functions.Numerous studies have indicated that AD patients often experience complex visual impairment,which may even occur before cognitive impairment.In this review,we introduce the research progress on the clinical symptoms of visual impairment,changes in the visual system,mechanisms underlying visual impairment,ocular biomarkers,and therapeutic interventions in AD patients.This comprehensive review aims to enhance our understanding of visual system alterations and highlight the potential significance of visual impairment as an early screening tool for identifying and intervening in AD.Ultimately,this knowledge can serve as a foundation for the early diagnosis and treatment of AD.