Evaluation of the safety of radial artery puncture in neurointerventional surgery in elderly patients aged 75 years and older
Objective To compare the safety of radial artery puncture in elderly patients aged 75 years and older who are undergoing neurointerventional procedures.Methods A single-center retrospective study was conducted,involving 350 elderly patients aged 75 years and older who received neurointerventional treatment at Beijing Tiantan Hospital,Capital Medical University,from June to December 2022.The participants were divided into two groups based on the puncture site:femoral artery puncture and radial artery puncture.The safety indicators compared between the two groups included puncture failure,changes in puncture site,general puncture complications(such as subcutaneous bleeding,puncture site hematoma,and vasospasm),severe puncture complications(including distal limb ischemia and pseudoaneurysm),and lower limb venous thrombosis.Multivariate Logistic regression analysis was conducted to evaluate the impact of different puncture methods on the occurrence of complications.Results Among the 350 patients,280 underwent femoral artery puncture,while 70 underwent radial artery puncture.There were no statistically significant differences in baseline characteristics between the two groups(all P>0.05).The proportions of patients using antiplatelet drugs prior to surgery,puncture failure rates,rates of change in puncture sites,and the incidence of severe complications-including distal limb ischemia and pseudoaneurysm-were not significantly different between the two groups(x2=2.051,0.075,0.588,3.175;P=0.152,0.784,0.443,0.075).In the femoral artery puncture group,20.4%(57 cases)of patients experienced general puncture complications(including subcutaneous bleeding,puncture site hematoma,and vasospasm),whereas only 8.6%(6 cases)in the radial artery puncture group experienced such complications,revealing a statistically significant difference between the two groups(x2=5.720,P=0.022).Multivariate Logistic regression analysis indicated that,compared to femoral artery puncture,radial artery puncture was associated with a reduced risk of all complications(OR=0.272,95%CI:0.139-0.532,P<0.001),general puncture complications(OR=0.375,95%CI:0.153-0.919,P=0.032)and lower limb venous thrombosis(OR=0.219,95%CI:0.050-0.954,P=0.043).Conclusions In elderly patients aged 75 years and older who are undergoing neurointerventional procedures,radial artery puncture is associated with a reduced incidence of general puncture complications and lower limb venous thrombosis when compared to femoral artery puncture,indicating a superior safety profile.