Comparative study on ultrasonic images of elderly-onset versus young-onset rheumatoid arthritis
Objective To compare the clinical and ultrasonic features of elderly-onset rheumatoid arthritis(EORA)and young-onset rheumatoid arthritis(YORA).Methods A total of 104 patients diagnosed with rheumatoid arthritis were categorized into two groups based on their age of onset:the EORA group,consisting of 70 patients,and the YORA group,consisting of 34 patients.A comparative analysis was conducted on the clinical manifestations,laboratory findings,and ultrasonic images of patients in these two groups.Results The male ratio in the EORA group was significantly higher than that in the YORA group(24.3％vs.8.8％,P=0.048).There were no statistical differences in the course of disease,DAS28,ESR,CRP,RF,and anti-CCP antibody positive rates between the two groups(P＞0.05)when compared with the YORA group.The incidence of osteoarthritis and osteoporosis in the EORA group was significantly higher than that in the YORA group(P=0.018,P=0.011).Ultrasonic results revealed a significantly higher incidence of phalangeal bone erosion in the EORA group compared to the YORA group(14.9％vs.4.3％,P＜0.01).Binary logistic regression analysis indicated that different age groups,disease duration,osteoarthritis,and osteoporosis did not have an effect on the ultrasonic changes of synovial hyperplasia,tendonitis,tenosynovitis,and bone erosion in RA patients.Conclusions There is no significant difference in the clinical disease activity and disease progression between EORA group and YORA group.Additionally,the pattern of joint inflammation involvement is similar in both groups.Ultrasound examinations revealed a higher incidence of bone erosion in finger joints of EORA patients compared to YORA patients.
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