Research progress on pathogenesis of inflammatory bowel disease and stem cell therapy in the elderly
As China enters the aging era,the incidence rate and prevalence of inflammatory bowel disease(IBD)in the elderly have increased.The relationship between aging and inflammation appears to be more significant in elderly individuals with IBD.However,most current studies focus on describing the clinical characteristics of the disease,with limited research on its pathogenesis and treatment.In this review,we summarize the differences in clinical characteristics and treatment between elderly individuals with IBD and young individuals.We also discuss the impact of aging on elderly IBD and explore the possibility of stem cell transplantation therapy as a new approach for clinical management.Our aim is to provide fresh insights for the treatment of elderly IBD.