The role of muscle-brain axis in the relationship between sarcopenia and cognitive impairment in the elderly
Frailty is a geriatric syndrome associated with aging,which is characterized by a decrease in the ability to stress and maintain homeostasis after the loss of physiological reserve function,resulting in an increased risk of falls,disability,and even death.Cognitive impairment is a disorder of cognitive function due to a variety of causes,between normal aging and dementia.In the early stages,frailty is a certain reversibility.As the core of physical frailty,sarcopenia has been a research hotspot in recent years.With the deep research on sarcopenia,researchers have found that is closely related to cognitive disorder.Muscle-brain axis may play a role in sarcopenia and cognitive impairment.This article illustrates its possible mechanisms at the crossroad of sarcopenia and cognitive disorder,and to provide reference for exploring new targets for intervention of sarcopenia and cognitive impairment.
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维普
