Research progress of cardiovascular disease risk prediction models among patients with chronic kidney disease
Patients with chronic kidney disease(CKD)have a relatively high risk of cardiovascular disease(CVD).Risk stratification guided by CVD risk prediction models is essential for managing CKD populations.We reviewed the outcome events,predictive variables,modeling methods,and predictive performance of CVD risk prediction models in CKD populations.We found a large variability in predictive outcomes,number of predictors,and sample sizes across studies.The models tended to overestimate the CVD risk of CKD populations.There are few independently validated or constructed CVD risk prediction models for CKD populations in developing countries,and in particular,there is a lack of independent external validation studies of model calibration.Future studies should comply with the reporting standards of risk prediction models to better support the application of CVD risk prediction models for CKD populations.
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