Glucocorticoid hypersensitivity syndrome: A case report and review of literature
叶小珍 1许一新 1杨新怡 1王燕燕 1邵加庆 1周丽斌
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作者信息
1. 中国人民解放军东部战区总医院内分泌科，南京 210002
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摘要
本文报道1例具有典型库欣综合征临床表现而血皮质醇水平极低的糖皮质激素过度敏感综合征，经过糖皮质激素受体拮抗剂米非司酮治疗后患者的库欣症状明显缓解，血皮质醇水平恢复正常。本例报道旨在提高临床医师对糖皮质激素过度敏感综合征的认识。 This article reports a patient with typical Cushing syndrome′s manifestations and extremely low plasma cortisol level, indicating glucocorticoid hypersensitivity syndrome. After treatment with the glucocorticoid receptor antagonist mifepristone, the patient′s Cushing symptoms were significantly relieved, and cortisol levels returned to normal. The aim of this report is to enhance clinical awareness among physicians regarding glucocorticoid hypersensitivity syndrome.
Abstract
This article reports a patient with typical Cushing syndrome′s manifestations and extremely low plasma cortisol level, indicating glucocorticoid hypersensitivity syndrome. After treatment with the glucocorticoid receptor antagonist mifepristone, the patient′s Cushing symptoms were significantly relieved, and cortisol levels returned to normal. The aim of this report is to enhance clinical awareness among physicians regarding glucocorticoid hypersensitivity syndrome.
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